HAMAP rule MF_00661

General rule information [?]

Accession	MF_00661
Dates	26-JUN-2003 (Created) 26-JAN-2023 (Last updated, Version 25)
Name	DEAD_helicase_RhlB
Scope(s)	Bacteria Pseudomonadota
Template(s)	P0A8J8 (RHLB_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00661 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RHLB
RecName: Full=ATP-dependent RNA helicase RhlB;<br />                  EC=<a href="https://enzyme.expasy.org/EC/3.6.4.13">3.6.4.13</a>;
Gene name	Name=rhlB;

Comments [?]

FUNCTION	DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
CATALYTIC ACTIVITY	Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
case <OC:Gammaproteobacteria>
SUBUNIT	Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
end case
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the DEAD box helicase family. RhlB subfamily.

Keywords [?]

ATP-binding
Cytoplasm
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a>
Hydrolase
Nucleotide-binding
RNA-binding

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0003724; Molecular function:RNA helicase activity

GO:0003723; Molecular function:RNA binding

GO:0006401; Biological process:RNA catabolic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]