HAMAP rule MF_01036
General rule information
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| Accession | MF_01036 |
| Dates | 18-NOV-2002 (Created)
1-JUN-2023 (Last updated, Version 25) |
| Name | RNase_II |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P30850 (RNB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01036 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RNB |
| Protein name | RecName: Full=Exoribonuclease 2; EC=3.1.13.1; AltName: Full=Exoribonuclease II; Short=RNase II; Short=Ribonuclease II; |
| Gene name | Name=rnb; |
Comments
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| FUNCTION | Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. |
| CATALYTIC ACTIVITY | Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=3.1.13.1; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the RNR ribonuclease family. RNase II subfamily. |
Keywords
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Gene Ontology
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| GO:0008859; Molecular function:exoribonuclease II activity |
| GO:0006402; Biological process:mRNA catabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00575; S1; 1; |
| Pfam | PF00773; RNB; 1; |
| NCBIfam | TIGR00358; 3_prime_RNase; 1; |
| NCBIfam | TIGR02062; RNase_B; 1; |
| PROSITE | PS01175; RIBONUCLEASE_II; 1; |
| PROSITE | PS50126; S1; 1; |
Features
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| From: RNB_HAEIN (P44440) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | 576 | 658 | /note="S1 motif" | |||||||||
Additional information
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| Size range | 644-678 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |