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HAMAP rule MF_01045

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General rule information [?]

Accession MF_01045
Dates 13-FEB-2003 (Created)
1-JUN-2023 (Last updated, Version 20)
Name D_Cys_desulfhydr
Scope(s) Bacteria
Enterobacterales
Template(s) P76316 (DCYD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01045 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DCYD
Protein name RecName: Full=D-cysteine desulfhydrase;
                 EC=4.4.1.15;
Gene name Name=dcyD;

Comments [?]

FUNCTIONCatalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
CATALYTIC ACTIVITY Reaction=D-cysteine + H2O = H(+) + hydrogen sulfide + NH4(+) + pyruvate; Xref=Rhea:RHEA:11268, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:29919, ChEBI:CHEBI:35236; EC=4.4.1.15;
case <FT:1>
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
end case
SUBUNITHomodimer.
SIMILARITYBelongs to the ACC deaminase/D-cysteine desulfhydrase family.

Keywords [?]

Lyase
case <FT:1>
Pyridoxal phosphate
end case

Gene Ontology [?]

GO:0019148; Molecular function:D-cysteine desulfhydrase activity
GO:0046416; Biological process:D-amino acid metabolic process

Cross-references [?]

Pfam PF00291; PALP; 1;
NCBIfam TIGR01275; ACC_deam_rel; 1;

Features [?]

From: DCYD_ECOLI (P76316)
Key From To Description Tag Condition FTGroup
MOD_RES 51 51 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 327-330 amino acids
Related rules None
Fusion Nter: None Cter: None



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