Annotation rule MF_01216
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General rule information [?]

Accession MF_01216
Dates 24-JUN-2002 (Created)
7-NOV-2017 (Last updated, Version 32)
Name Azoreductase_type1
Scope Bacteria
Template P41407 (AZOR_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=FMN-dependent NADH-azoreductase;
AltName: Full=Azo-dye reductase;
AltName: Full=FMN-dependent NADH-azo compound oxidoreductase;
Gene name

Comments [?]

Function Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity.
Cofactor FMN
Note: Binds 1 FMN per subunit.
Subunit Homodimer.
Similarity Belongs to the azoreductase type 1 family.

Keywords [?]

Gene Ontology [?]

GO:0008752; Molecular function: FMN reductase activity.
GO:0009055; Molecular function: electron transfer activity.
GO:0010181; Molecular function: FMN binding.
GO:0016652; Molecular function: oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor.

Cross-references [?]

Pfam PF02525; Flavodoxin_2; 1;

Features [?]

case <OC:Enterobacterales>
From: AZOR_ECOLI (P41407)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     16     18       FMN     S-Q-S  
NP_BIND     96     99       FMN     M-Y-N-F  
NP_BIND     140     145       FMN     S-R-G-G-I-H  
BINDING     10     10       FMN     S  
end case

Additional information [?]

Size range 192-220 amino acids
Related rules None
Fusion None
Comments Divergent STRCO and first copy in CLOAB and CLOPE; sequences not included in alignment and not taken into account in size range. In some species there are many duplicates.