HAMAP rule MF_01306
General rule information
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| Accession | MF_01306 |
| Dates | 3-DEC-2002 (Created)
22-SEP-2023 (Last updated, Version 36) |
| Name | Ribosomal_uS4 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | P81288 (RS4_GEOSE); P21466 (RS4_BACSU); P0A7V8 (RS4_ECOLI); O54297 (RS4_SALTY); P80373 (RS4_THET8); P48270 (RR4_CHLRE); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01306_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01306_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RS4 |
| Protein name | RecName: Full=Small ribosomal subunit protein uS4; |
| Gene name | Name=rpsD; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RS4 |
| Protein name | RecName: Full=Small ribosomal subunit protein uS4; |
| Gene name | Name=rpsD; Synonyms=rps4; |
| else case <OC:Archaea> | |
| Identifier | RS4 |
| Protein name | RecName: Full=Small ribosomal subunit protein uS4; |
| Gene name | Name=rps4; |
| else case <OG:Chloroplast> | |
| Identifier | RR4 |
| Protein name | RecName: Full=Small ribosomal subunit protein uS4c; |
| Gene name | Name=rps4; |
| end case | |
Comments
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| FUNCTION | One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. |
| FUNCTION | With S5 and S12 plays an important role in translational accuracy. |
| SUBUNIT | Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity. |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uS4 family. |
Keywords
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Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00163; Ribosomal_S4; 1; |
| Pfam | PF01479; S4; 1; |
| NCBIfam | TIGR01018; RpsD_arch; 1; |
| NCBIfam | TIGR01017; RpsD_bact; 1; |
| PROSITE | PS00632; RIBOSOMAL_S4; 1; |
| PROSITE | PS50889; S4; 1; |
Features
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Additional information
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| Size range | 159-219 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Some plastid-encoded rps4 sequences (EIMTE, HELSJ, STIHE, TOXGO), as well as CARRP and NEOSM are quite divergent and thus have been made atypical. The second and third copies in the Clostridia have also been made atypical. In AZOSB the second copy is truncated and probably not functional. |