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HAMAP rule MF_01325

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General rule information [?]

Accession MF_01325
Dates 4-FEB-2004 (Created)
22-SEP-2023 (Last updated, Version 34)
Name Ribosomal_uL3
Scope(s) Bacteria
Archaea
Plastid
Template(s) Q5SHN8 (RL3_THET8); P20279 (RL3_HALMA); Q9RXK2 (RL3_DEIRA); P60438 (RL3_ECOLI); [ Recover all ]
Triggered by
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01325_B (Get profile general information and statistics)
end case
case c? <OC:Archaea>
HAMAP; MF_01325_A (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
Identifier RL3
Protein name RecName: Full=Large ribosomal subunit protein uL3;
Gene name Name=rplC;
else case <OC:Cyanobacteriota>
Identifier RL3
Protein name RecName: Full=Large ribosomal subunit protein uL3;
Gene name Name=rplC; Synonyms=rpl3;
else case <OC:Archaea>
Identifier RL3
Protein name RecName: Full=Large ribosomal subunit protein uL3;
Gene name Name=rpl3;
else case <OG:Chloroplast>
Identifier RK3
Protein name RecName: Full=Large ribosomal subunit protein uL3c;
Gene name Name=rpl3;
end case

Comments [?]

FUNCTIONOne of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
case <OC:Bacteria>
SUBUNITPart of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.
else case <OC:Archaea>
SUBUNITPart of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.
else case <OG:Chloroplast>
SUBUNITPart of the 50S ribosomal subunit.
SUBCELLULAR LOCATIONPlastid, chloroplast.
end case
case <OC:Pseudomonadota> and <FTTag:Methylation>
PTMMethylated by PrmB.
end case
SIMILARITYBelongs to the universal ribosomal protein uL3 family.

Keywords [?]


Gene Ontology [?]

GO:0019843; Molecular function:rRNA binding
GO:0006412; Biological process:translation
case <OG:Chloroplast>
GO:0009507; Cellular component:chloroplast
end case

Cross-references [?]

Pfam PF00297; Ribosomal_L3; 1;
PROSITE PS00474; RIBOSOMAL_L3; 1;
NCBIfam TIGR03626; L3_arch; 1;
NCBIfam TIGR03625; L3_bact; 1;

Features [?]

From: RL3_ECOLI (P60438)
Key From To Description Tag Condition FTGroup
case <OC:Pseudomonadota>
MOD_RES 150 150 /note="N5-methylglutamine" Methylation Q
end case

Additional information [?]

Size range 310-399 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The Epsilonproteobacteria form a distinct sub-group within this family; they have been made atypical.



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