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HAMAP rule MF_01494

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General rule information [?]

Accession MF_01494
Dates 17-JUN-2014 (Created)
13-JAN-2023 (Last updated, Version 7)
Name DEAD_helicase_CshB
Scope(s) Bacteria
Bacillota
Template(s) P54475 (CSHB_BACSU); Q818H2 (CSHB_BACCR); Q8Y755 (CSHB_LISMO); [ Recover all ]
Triggered by HAMAP; MF_01494 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CSHB
RecName: Full=DEAD-box ATP-dependent RNA helicase CshB;<br /> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;EC=<a href="https://enzyme.expasy.org/EC/3.6.4.13">3.6.4.13</a>;
Gene name Name=cshB;

Comments [?]

FUNCTIONProbable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
CATALYTIC ACTIVITY Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the DEAD box helicase family. CshB subfamily.

Keywords [?]

ATP-binding
Cytoplasm
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a>
Hydrolase
Nucleotide-binding
RNA-binding
Stress response

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003724; Molecular function:RNA helicase activity
GO:0003723; Molecular function:RNA binding
GO:0006401; Biological process:RNA catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS51192; HELICASE_ATP_BIND_1; 1;
PROSITE PS51194; HELICASE_CTER; 1;
PROSITE PS51195; Q_MOTIF; 1;
Pfam PF00270; DEAD; 1;
Pfam PF00271; Helicase_C; 1;

Features [?]


Additional information [?]

Size range 425-465 amino acids
Related rules MF_01493
Fusion Nter: None Cter: None



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