HAMAP rule MF_01728
General rule information
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| Accession | MF_01728 |
| Dates | 14-MAY-2007 (Created)
1-JUN-2023 (Last updated, Version 23) |
| Name | ABC_ATPase_TM_NdvA |
| Scope(s) |
Bacteria Hyphomicrobiales |
| Template(s) | P18767 (NDVA_RHIME); [ Recover all ] |
| Triggered by |
PROSITE; PS51317 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NDVA |
| Protein name | RecName: Full=Beta-(1-->2)glucan export ATP-binding/permease protein NdvA; EC=7.5.2.3; |
| Gene name | Name=ndvA; |
Comments
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| FUNCTION | Involved in Beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. |
| CATALYTIC ACTIVITY | Reaction=[(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O = [(1->2)-beta-D- glucosyl](n)(out) + ADP + H(+) + phosphate; Xref=Rhea:RHEA:18453, Rhea:RHEA-COMP:11881, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:27517, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.3; |
| SUBUNIT | Homodimer. |
| DOMAIN | In NdvA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused. |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ABC transporter superfamily. Beta- (1-->2)glucan exporter (TC 3.A.1.108.1) family. |
Keywords
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| ATP-binding | |
| Nucleotide-binding | |
| Cell membrane | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Membrane | |
| Sugar transport | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
| Transmembrane | |
| Transport | |
| Transmembrane helix | |
Gene Ontology
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| GO:0008643; Biological process:carbohydrate transport | |
| GO:0015441; Molecular function:ABC-type beta-glucan transporter activity | |
| case <OCellular component:Bacteria> | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| Pfam | PF00664; ABC_membrane; 1; |
| NCBIfam | TIGR01192; ChvA; 1; |
| PROSITE | PS50929; ABC_TM1F; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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Additional information
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| Size range | 550-630 amino acids |
| Related rules |
PRU01700 |
| Fusion | Nter: None Cter: None |