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HAMAP rule MF_01859

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General rule information [?]

Accession MF_01859
Dates 11-FEB-2009 (Created)
17-FEB-2023 (Last updated, Version 15)
Name 23SrRNA_methyltr_G
Scope(s) Bacteria
Kitasatosporales
Pseudomonadota
Template(s) P42596 (RLMG_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01859 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RLMG
Protein name RecName: Full=Ribosomal RNA large subunit methyltransferase G;
                 EC=2.1.1.174;
AltName: Full=23S rRNA m2G1835 methyltransferase;
AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RlmG;
Gene name Name=rlmG;

Comments [?]

FUNCTIONSpecifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
CATALYTIC ACTIVITY Reaction=guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42744, Rhea:RHEA-COMP:10217, Rhea:RHEA-COMP:10218, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.174;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the methyltransferase superfamily. RlmG family.

Keywords [?]


Gene Ontology [?]

GO:0008990; Molecular function:rRNA (guanine-N2-)-methyltransferase activity
GO:0031167; Biological process:rRNA methylation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF05175; MTS; 1;
PRINTS PR00508; S21N4MTFRASE; 1;
PIRSF PIRSF037565; RRNA_m2G_Mtase_RsmD_prd; 1;

Features [?]


Additional information [?]

Size range 369-421 amino acids
Related rules None
Fusion Nter: None Cter: None



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