HAMAP rule MF_02099
General rule information
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| Accession | MF_02099 |
| Dates | 16-NOV-2017 (Created)
1-JUN-2023 (Last updated, Version 6) |
| Name | HybF_subfam |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P0A703 (HYBF_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_02099 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HYBF |
| Protein name | RecName: Full=Hydrogenase maturation factor HybF; |
| Gene name | Name=hybF; |
Comments
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| FUNCTION | Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. |
| SIMILARITY | Belongs to the HypA/HybF family. HybF subfamily. |
Keywords
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| Metal-binding | |
| Nickel | |
| case <FTGroup:1> | |
| Zinc | |
| end case | |
Gene Ontology
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| GO:0016151; Molecular function:nickel cation binding | |
| case <FTGroup:1> | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
| GO:0036211; Biological process:protein modification process | |
Cross-references
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| PROSITE | PS01249; HYPA; 1; |
| Pfam | PF01155; HypA; 1; |
| NCBIfam | TIGR00100; hypA; 1; |
| PIRSF | PIRSF004761; Hydrgn_mat_HypA; 1; |
Features
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| From: HYBF_ECOLI (P0A703) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 2 | 2 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786" |
H | ||||||||
| BINDING | 3 | 3 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786" |
E | ||||||||
| BINDING | 73 | 73 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 76 | 76 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 89 | 89 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 92 | 92 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
Additional information
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| Size range | 110-132 amino acids |
| Related rules |
MF_00213 |
| Fusion | Nter: None Cter: None |
| Comments | See MF_00213 for HypA. |