HAMAP rule MF_00076
General rule information
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Accession | MF_00076 |
Dates | 14-JUN-2002 (Created) 20-NOV-2019 (Last updated, Version 33) |
Name | HisB |
Scope | Bacteria
Archaea |
Template | Q02134 (HIS7_LACLA) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Catalytic activity | RHEA:11040: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O
EC 4.2.1.19 |
Pathway | Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the imidazoleglycerol-phosphate dehydratase family. |
Keywords
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Gene Ontology
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GO:0004424; Molecular function: imidazoleglycerol-phosphate dehydratase activity.
GO:0000105; Biological process: histidine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0000105; Biological process: histidine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Additional information
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Size range | 176-216 amino acids |
Related rules | MF_01022 (HIS7 supersedes the current rule) |
Fusion | None |
Comments | Longer N-terminal in NEIMA and NEIMB; not shown in alignment and not taken into account in size range. See MF_01022 for bifunctional hisB. |