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Annotation rule MF_00145
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General rule information [?]

Accession MF_00145
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 36)
Name Phosphoglyc_kinase
Scope
Bacteria
Archaea
Templates P18912 (PGK_GEOSE); Q8GIZ5 (PGK_LACDL); P36204 (PGKT_THEMA); P09403 (PGK_THET8); P61884 (PGK_PYRWO): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PGK
Protein name
RecName: Full=Phosphoglycerate kinase;
EC 2.7.2.3;
Gene name
pgk

Comments [?]

Catalytic activity RHEA:14801: (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP
EC 2.7.2.3
Pathway Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
Subunit Monomer.
Subcellular location Cytoplasm.
Similarity Belongs to the phosphoglycerate kinase family.

Keywords [?]

case <FT:10>
Acetylation
end case
Cytoplasm
ATP-binding
Glycolysis
Kinase
Nucleotide-binding
Transferase
case <FT:11> or <FT:12>
Phosphoprotein
end case

Gene Ontology [?]

GO:0004618; Molecular function: phosphoglycerate kinase activity.
GO:0006096; Biological process: glycolytic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00162; PGK; 1;
PRINTS PR00477; PHGLYCKINASE; 1;
PROSITE PS00111; PGLYCERATE_KINASE; 1;

Features [?]

From: PGKT_THEMA (P36204)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     353     356       ATP     G-G-[DEH]-[STAILFM]  
REGION     21     23       Substrate binding     D-[LFMYVI]-N  
REGION     59     62       Substrate binding     [HQR]-x-[GSDRK]-[RGKNDP]  
BINDING (Optional)     36     36       Substrate     R  
BINDING (Optional)     118     118       Substrate     R  
BINDING (Optional)     151     151       Substrate     R  
BINDING (Optional)     201     201       ATP     K  
BINDING (Optional)     293     293       ATP; via carbonyl oxygen     G  
BINDING (Optional)     324     324       ATP     E  
case <OC:Escherichia> or <OC:Shigella>
From: PGK_ECOLI (P0A799)
MOD_RES     84     84       N6-acetyllysine     K  
end case
case <OC:Bacillaceae>
From: PGK_BACSU (P40924)
MOD_RES     183     183       Phosphoserine     S  
MOD_RES     299     299       Phosphothreonine     T  
end case

Additional information [?]

Size range 385-419 amino acids
Related rules None
Fusion Nter: None; Cter: MF_00147 (tpiA), <Unknown>


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