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Annotation rule MF_00285
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General rule information [?]

Accession MF_00285
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 58)
Name KdpB
Scope
Bacteria
Archaea
Template P03960 (KDPB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KDPB
Protein name
RecName: Full=Potassium-transporting ATPase ATP-binding subunit;
EC 7.2.2.6;
AltName: Full=ATP phosphohydrolase [potassium-transporting] B chain;
AltName: Full=Potassium-binding and translocating subunit B;
AltName: Full=Potassium-translocating ATPase B chain;
Gene name
kdpB

Comments [?]

Function Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.
Catalytic activity RHEA:16777: ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate
EC 7.2.2.6
Subunit The system is composed of three essential subunits: KdpA, KdpB and KdpC.
case defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else
Subcellular location Cell membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Translocase
Transport
Ion transport
Potassium
Potassium transport
Membrane
Transmembrane
Phosphoprotein
Magnesium
Metal-binding
ATP-binding
Nucleotide-binding
Transmembrane helix

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0008556; Molecular function: potassium transmembrane transporter activity, phosphorylative mechanism.
GO:0006813; Biological process: potassium ion transport.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF00122; E1-E2_ATPase; 1;
PF00702; Hydrolase; 1;
PRINTS PR00119; CATATPASE; 1;
PR00120; HATPASE; 1;
TIGRFAMs TIGR01494; ATPase_P-type; 1;
TIGR01497; KdpB; 1;
PROSITE PS00154; ATPASE_E1_E2; 1;

Computed features [?]

General Transmembrane; -; 7; trigger=yes;

Features [?]

From: KDPB_ECOLI (P03960)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     377     384       ATP     F-x-[AS]-x-[TS]-[RK]-x-S  
ACT_SITE     307     307       4-aspartylphosphate intermediate     D  
METAL     518     518       Magnesium     D  
METAL     522     522       Magnesium     D  
BINDING (Optional)     344     344       ATP     D  
BINDING (Optional)     348     348       ATP     E  
BINDING (Optional)     395     395       ATP     K  

Additional information [?]

Size range 620-760 amino acids
Related rules None
Fusion None
Comments The S.typhi ortholog has a 112 amino acid internal deletion and is not used in the alignments.


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