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Annotation rule MF_00285 |
General rule information
[?]
Accession |
MF_00285 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 58) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Potassium-transporting ATPase ATP-binding subunit;
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EC 7.2.2.6;
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AltName:
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Full=ATP phosphohydrolase [potassium-transporting] B chain;
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AltName:
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Full=Potassium-binding and translocating subunit B;
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AltName:
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Full=Potassium-translocating ATPase B chain;
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Function |
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. |
Catalytic activity |
RHEA:16777: ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate
EC 7.2.2.6
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Subunit |
The system is composed of three essential subunits: KdpA, KdpB and KdpC. |
case defined <Property:Membrane> and <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
else
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0008556; Molecular function: potassium transmembrane transporter activity, phosphorylative mechanism.
GO:0006813; Biological process: potassium ion transport.
GO:0005887; Cellular component: integral component of plasma membrane.
General |
Transmembrane; -; 7; trigger=yes; |
From: KDPB_ECOLI (P03960) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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NP_BIND
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377
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384
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ATP
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F-x-[AS]-x-[TS]-[RK]-x-S
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ACT_SITE
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307
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307
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4-aspartylphosphate intermediate
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D
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METAL
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518
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518
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Magnesium
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D
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METAL
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522
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522
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Magnesium
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D
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BINDING (Optional)
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344
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344
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ATP
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D
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BINDING (Optional)
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348
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348
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ATP
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E
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BINDING (Optional)
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395
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395
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ATP
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K
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Additional information
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Size range |
620-760 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
The S.typhi ortholog has a 112 amino acid internal deletion and is not used in the alignments. |