 |
|
| Annotation rule MF_00394 |
General rule information
[?]
| Accession | MF_00394 |
| Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 34) |
| Name | NAD_Glyc3P_dehydrog |
| Scope | Bacteria
Archaea |
| Template | O29390 (GPDA_ARCFU) |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||||||
| Gene name |
|
Comments
[?]
| Catalytic activity | RHEA:11092: NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH
EC 1.1.1.94 |
| RHEA:11096: NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH
EC 1.1.1.94 |
|
| Subcellular location | Cytoplasm. |
| Pathway | Membrane lipid metabolism; glycerophospholipid metabolism. |
| Similarity | Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. |
Keywords
[?]
Cytoplasm
Lipid biosynthesis
Lipid metabolism
Phospholipid biosynthesis
Phospholipid metabolism
NAD
Oxidoreductase
Lipid biosynthesis
Lipid metabolism
Phospholipid biosynthesis
Phospholipid metabolism
NAD
Oxidoreductase
Gene Ontology
[?]
GO:0047952; Molecular function: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity.
GO:0046167; Biological process: glycerol-3-phosphate biosynthetic process.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0046167; Biological process: glycerol-3-phosphate biosynthetic process.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
| Pfam | PF07479; NAD_Gly3P_dh_C; 1; |
| PF01210; NAD_Gly3P_dh_N; 1; | |
| PIRSF | PIRSF000114; Glycerol-3-P_dh; 1; |
| PRINTS | PR00077; GPDHDRGNASE; 1; |
| PROSITE | PS00957; NAD_G3PDH; 1; |
Features
[?]
| From: GPDA_ECOLI (P0A6S7) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| NP_BIND | 12 | 17 | NAD | |||||||||
| REGION | 259 | 260 | Substrate binding | R-N | ||||||||
| ACT_SITE | 195 | 195 | Proton acceptor | K | ||||||||
| BINDING | 110 | 110 | NAD; via amide nitrogen | K | ||||||||
| BINDING | 110 | 110 | Substrate | K | ||||||||
| BINDING | 143 | 143 | NAD; via amide nitrogen | [AS] | ||||||||
| BINDING | 259 | 259 | NAD | R | ||||||||
| BINDING | 285 | 285 | NAD | E | ||||||||
Additional information
[?]
| Size range | 297-369 amino acids |
| Related rules | None |
| Fusion | None |