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Annotation rule MF_00455
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General rule information [?]

Accession MF_00455
Dates 24-SEP-2001 (Created)
18-NOV-2019 (Last updated, Version 38)
Name Xylose_isom_A
Scope
Bacteria
Templates P12851 (XYLA_ACTM4); P12070 (XYLA_ARTS7); P54272 (XYLA_BACSW); P00944 (XYLA_ECOLI); P15587 (XYLA_STROL): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
XYLA
Protein name
RecName: Full=Xylose isomerase;
EC 5.3.1.5;
Gene name
xylA

Comments [?]

Catalytic activity RHEA:22816: D-xylose = D-xylulose
EC 5.3.1.5
Cofactor Mg(2+)
Note: Binds 2 magnesium ions per subunit.
Subunit Homotetramer.
Subcellular location Cytoplasm.
Similarity Belongs to the xylose isomerase family.

Keywords [?]


Gene Ontology [?]

GO:0000287; Molecular function: magnesium ion binding.
GO:0009045; Molecular function: xylose isomerase activity.
GO:0042732; Biological process: D-xylose metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01261; AP_endonuc_2; 1;
PRINTS PR00688; XYLOSISMRASE; 1;
TIGRFAMs TIGR02630; Xylose_isom_A; 1;
PROSITE PS51415; XYLOSE_ISOMERASE; 1;

Features [?]

case <OC:Actinomycetales> or <OC:Deinococci>
From: XYLA_ACTM4 (P12851)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     54     54             H  
ACT_SITE     57     57             [DE]  
METAL     181     181       Magnesium 1     E  
METAL     217     217       Magnesium 1     E  
METAL     217     217       Magnesium 2     E  
METAL     220     220       Magnesium 2     H  
METAL     245     245       Magnesium 1     D  
METAL     255     255       Magnesium 2     D  
METAL     257     257       Magnesium 2     D  
METAL     292     292       Magnesium 1     D  
end case
case not <OC:Actinomycetales> and not <OC:Deinococci>
From: XYLA_ECOLI (P00944)
ACT_SITE     101     101             H  
ACT_SITE     104     104             [DE]  
METAL     232     232       Magnesium 1     E  
METAL     268     268       Magnesium 1     E  
METAL     268     268       Magnesium 2     E  
METAL     271     271       Magnesium 2     H  
METAL     296     296       Magnesium 1     D  
METAL     307     307       Magnesium 2     D  
METAL     309     309       Magnesium 2     D  
METAL     339     339       Magnesium 1     D  
end case

Additional information [?]

Size range 386-449 amino acids
Related rules None
Fusion None