HAMAP rule MF_00476
General rule information
[?]
Accession | MF_00476 |
Dates | 26-OCT-2001 (Created) 19-NOV-2022 (Last updated, Version 36) |
Name | NikR |
Scope | Bacteria
Archaea |
Template | P0A6Z6 (NIKR_ECOLI) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
case <OC:Enterobacterales>
Protein name |
|
Gene name |
|
else
Protein name |
|
end case
Comments
[?]
case <OC:Enterobacterales>
Function | Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. |
else
Function | Transcriptional regulator. |
end case
case <FTGroup:1>
Cofactor | Ni(2+) Note: Binds 1 nickel ion per subunit. |
end case
case <OC:Enterobacterales>
Subunit | Homotetramer. |
end case
Similarity | Belongs to the transcriptional regulatory CopG/NikR family. |
Keywords
[?]
case <OC:Enterobacterales>
end case
case <FTGroup:1>
end case
Gene Ontology
[?]
GO:0016151; Molecular function: nickel cation binding.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0006355; Biological process: regulation of DNA-templated transcription.
Cross-references
[?]
Features
[?]
From: NIKR_ECOLI (P0A6Z6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 76 | 76 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786 | H | 1 | |||||||
BINDING | 87 | 87 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786 | H | 1 | |||||||
BINDING | 89 | 89 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786 | H | 1 | |||||||
BINDING | 95 | 95 | /ligand="Ni(2+)" /ligand_id="ChEBI:CHEBI:49786 | C | 1 |
Additional information
[?]
Size range | 127-148 amino acids |
Related rules | None |
Fusion | None |