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HAMAP rule MF_00493

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General rule information [?]

Accession MF_00493
Dates 30-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 30)
Name Transaldolase_2
Scope
Bacteria
Template P48983 (TAL2_NOSP7)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TAL
Protein name
RecName: Full=Transaldolase;
EC 2.2.1.2;
Gene name
tal

Comments [?]

Function Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic activity RHEA:17053: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
EC 2.2.1.2
Pathway Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Subcellular location Cytoplasm.
Similarity Belongs to the transaldolase family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004801; Molecular function: transaldolase activity.
GO:0006098; Biological process: pentose-phosphate shunt.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00923; Transaldolase; 1;
PROSITE PS00958; TRANSALDOLASE_2; 1;
PS01054; TRANSALDOLASE_1; 1;
NCBIfam TIGR00876; tal_mycobact; 1;

Features [?]

From: TAL_MYCTU (P9WG33)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     143     143       Schiff-base intermediate with substrate     K  

Additional information [?]

Size range 316-381 amino acids
Related rules MF_00492 (TAL); MF_00494 (TAL); MF_00496 (FSA)
Fusion None