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Annotation rule MF_00550
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General rule information [?]

Accession MF_00550
Dates 26-APR-2002 (Created)
18-NOV-2019 (Last updated, Version 32)
Name Aminopeptidase_M20
Scope
Bacteria
Templates P26311 (PEPT_SALTY); P55179 (PEPT_BACSU); P29745 (PEPT_ECOLI); P0C2T7 (PEPT_LACLC); Q9L4G1 (PEPT_LACHE); P81207 (PEPT_FUSNP); Q76HM7 (PEPT2_LACLC); Q76HM5 (PEPT_LACLL); Q84BV2 (PEPT_LACLH): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PEPT
Protein name
RecName: Full=Peptidase T;
EC 3.4.11.4;
AltName: Full=Aminotripeptidase;
Short=Tripeptidase;
AltName: Full=Tripeptide aminopeptidase;
Gene name
pepT

Comments [?]

Function Cleaves the N-terminal amino acid of tripeptides.
Catalytic activity Reaction=Release of the N-terminal residue from a tripeptide.; EC=3.4.11.4;
Cofactor Zn(2+)
Note: Binds 2 Zn(2+) ions per subunit.
Subcellular location Cytoplasm.
Similarity Belongs to the peptidase M20B family.

Keywords [?]


Gene Ontology [?]

GO:0045148; Molecular function: tripeptide aminopeptidase activity.
GO:0008270; Molecular function: zinc ion binding.
GO:0006508; Biological process: proteolysis.
GO:0043171; Biological process: peptide catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00758; ARGE_DAPE_CPG2_1; 1;
PS00759; ARGE_DAPE_CPG2_2; 1;
Pfam PF07687; M20_dimer; 1;
PF01546; Peptidase_M20; 1;
TIGRFAMs TIGR01882; Peptidase-T; 1;

Features [?]

From: PEPT_SALTY (P26311)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     80     80             D  
ACT_SITE     173     173       Proton acceptor     E  
METAL     78     78       Zinc 1     H  
METAL     140     140       Zinc 1     D  
METAL     140     140       Zinc 2     D  
METAL     174     174       Zinc 2     E  
METAL     196     196       Zinc 1     D  
METAL     379     379       Zinc 2     H  

Additional information [?]

Size range 406-413 amino acids
Related rules None
Fusion None