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Annotation rule MF_00601
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General rule information [?]

Accession MF_00601
Dates 17-NOV-2002 (Created)
26-FEB-2021 (Last updated, Version 22)
Name EutC
Scope
Bacteria
Archaea; Halobacteria
Templates P19265 (EUTC_SALTY); P19636 (EUTC_ECOLI): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
EUTC
case <OC:Bacteria>
Protein name
RecName: Full=Ethanolamine ammonia-lyase small subunit;
Short=EAL small subunit;
EC 4.3.1.7;
else case <OC:Archaea>
Protein name
RecName: Full=Putative ethanolamine ammonia-lyase small subunit;
Short=EAL small subunit;
EC 4.3.1.7;
end case
Gene name
eutC

Comments [?]

case <OC:Bacteria>
Function Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
else case <OC:Archaea>
Function May catalyze the deamination of various vicinal amino-alcohols to oxo compounds.Would allow this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
end case
Catalytic activity RHEA:15313: ethanolamine = acetaldehyde + NH4(+)
EC 4.3.1.7
Cofactor adenosylcob(III)alamin
Note: Binds between the large and small subunits
Pathway Amine and polyamine degradation; ethanolamine degradation.
Subunit The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.
case <OC:Bacteria>
Subcellular location Bacterial microcompartment.
end case
Similarity Belongs to the EutC family.

Keywords [?]

case <OC:Bacteria>
end case

Gene Ontology [?]

GO:0008851; Molecular function: ethanolamine ammonia-lyase activity.
GO:0009350; Cellular component: ethanolamine ammonia-lyase complex.
GO:0046336; Biological process: ethanolamine catabolic process.
GO:0031419; Molecular function: cobalamin binding.
case <OC:Bacteria>
GO:0031471; Cellular component: ethanolamine degradation polyhedral organelle.
end case

Cross-references [?]

Pfam PF05985; EutC; 1;
PIRSF PIRSF018982; EutC; 1;

Features [?]

From: EUTC_ECOLI (P19636)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     207     207       Adenosylcob(III)alamin; via amide nitrogen     V  
BINDING     228     228       Adenosylcob(III)alamin     E  
case not <OC:Firmicutes>
BINDING     258     258       Adenosylcob(III)alamin; via carbonyl oxygen     C  
end case

Additional information [?]

Size range 235-330 amino acids
Related rules None
Fusion None
Comments Both large and small subunits are found in Archaeal Halobacteria.