HAMAP rule MF_00607
General rule information
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Accession | MF_00607 |
Dates | 9-DEC-2002 (Created) 1-JUN-2023 (Last updated, Version 26) |
Name | 16SrRNA_methyltr_A |
Scope | Bacteria
Archaea |
Templates | P06992 (RSMA_ECOLI); P13956 (ERM_BACIU): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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case <OC:Bacteria>
Protein name |
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else case <OC:Archaea>
Protein name |
|
end case
Gene name |
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Comments
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case <OC:Bacteria>
Function | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. |
Catalytic activity | RHEA:19609: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine
EC 2.1.1.182 |
else case <OC:Archaea>
Function | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. |
end case
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. |
Keywords
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Gene Ontology
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GO:0016433; Molecular function: rRNA (adenine) methyltransferase activity.
GO:0000154; Biological process: rRNA modification.
GO:0005737; Cellular component: cytoplasm.
GO:0000154; Biological process: rRNA modification.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Features
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From: RSMA_ECOLI (P06992) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING (Optional) | 18 | 18 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [NH] | ||||||||
BINDING | 20 | 20 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [ILVM] | ||||||||
BINDING | 45 | 45 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | G | ||||||||
BINDING | 66 | 66 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | E | ||||||||
BINDING | 91 | 91 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | D | ||||||||
BINDING | 113 | 113 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | N |
Additional information
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Size range | 219-390 amino acids |
Related rules | None |
Fusion | None |