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Annotation rule MF_00607 |
Accession | MF_00607 |
Dates | 9-DEC-2002 (Created) 18-NOV-2019 (Last updated, Version 23) |
Name | 16SrRNA_methyltr_A |
Scope | Bacteria
Archaea |
Templates | P06992 (RSMA_ECOLI); P13956 (ERM_BACIU): [Recover all] |
Triggered by |
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Function | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. |
Catalytic activity | RHEA:19609: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine
EC 2.1.1.182 |
Function | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. |
From: RSMA_ECOLI (P06992) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING (Optional) | 18 | 18 | S-adenosyl-L-methionine; via carbonyl oxygen | [NH] | ||||||||
BINDING | 20 | 20 | S-adenosyl-L-methionine; via amide nitrogen | [ILVM] | ||||||||
BINDING | 45 | 45 | S-adenosyl-L-methionine; via carbonyl oxygen | G | ||||||||
BINDING | 66 | 66 | S-adenosyl-L-methionine | E | ||||||||
BINDING | 91 | 91 | S-adenosyl-L-methionine | D | ||||||||
BINDING | 113 | 113 | S-adenosyl-L-methionine | N |
Size range | 219-390 amino acids |
Related rules | None |
Fusion | None |