Home  |  Contact
Annotation rule MF_00617
Send feedback

General rule information [?]

Accession MF_00617
Dates 7-FEB-2003 (Created)
18-NOV-2019 (Last updated, Version 28)
Name MPGP_rel
Scope
Bacteria
Archaea
Templates O58690 (MPGP_PYRHO); P76329 (MPGP_ECOLI): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MPGP
Protein name
RecName: Full=Mannosyl-3-phosphoglycerate phosphatase;
Short=MPGP;
EC 3.1.3.70;
case <OC:Archaea>
Gene name
mngB
end case

Comments [?]

case <OC:Archaea>
Function Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG).
Pathway Carbohydrate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate biosynthesis; 2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route): step 2/2.
end case
Catalytic activity RHEA:19309: 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate
EC 3.1.3.70
Cofactor Mg(2+)
Subcellular location Cytoplasm.
Similarity Belongs to the HAD-like hydrolase superfamily. MPGP family.

Keywords [?]

Cytoplasm
Hydrolase
Magnesium
Metal-binding

Gene Ontology [?]

GO:0050531; Molecular function: mannosyl-3-phosphoglycerate phosphatase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF08282; Hydrolase_3; 1;
TIGRFAMs TIGR01484; HAD-SF-IIB; 1;
TIGR01486; HAD-SF-IIB-MPGP; 1;
TIGR02461; osmo_MPG_phos; 0-1;
TIGR02463; MPGP_rel; 0-1;

Features [?]

From: MPGP_PYRHO (O58690)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     8     8       Nucleophile     D  
METAL     8     8       Magnesium     D  
METAL     10     10       Magnesium; via carbonyl oxygen     D  
METAL (Optional)     169     169       Magnesium     S  
METAL     204     204       Magnesium     D  

Additional information [?]

Size range 242-281 amino acids
Related rules None
Fusion None


View rule in raw text format (no links)