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Annotation rule MF_00733
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General rule information [?]

Accession MF_00733
Dates 24-NOV-2003 (Created)
4-JUN-2021 (Last updated, Version 20)
Name RocA
Scope
Bacteria; Bacillales
Template P39634 (ROCA_BACSU)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ROCA
Protein name
RecName: Full=1-pyrroline-5-carboxylate dehydrogenase;
Short=P5C dehydrogenase;
EC 1.2.1.88;
AltName: Full=L-glutamate gamma-semialdehyde dehydrogenase;
Gene name
rocA

Comments [?]

Catalytic activity RHEA:30235: H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH
EC 1.2.1.88
Pathway Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.
Similarity Belongs to the aldehyde dehydrogenase family. RocA subfamily.

Keywords [?]

Oxidoreductase
NAD

Gene Ontology [?]

GO:0003842; Molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity.
GO:0006537; Biological process: glutamate biosynthetic process.

Cross-references [?]

Pfam PF00171; Aldedh; 1;
TIGRFAMs TIGR01237; D1pyr5carbox2; 1;
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1;
PS00687; ALDEHYDE_DEHYDR_GLU; 1;

Features [?]

From: ROCA_BACSU (P39634)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     286     286             E  
ACT_SITE     320     320             C  

Additional information [?]

Size range 514-515 amino acids
Related rules None
Fusion None


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