![]() |
|
Annotation rule MF_00812 |
Accession | MF_00812 |
Dates | 22-AUG-2005 (Created) 18-NOV-2019 (Last updated, Version 20) |
Name | Thiopur_methtran |
Scope | Bacteria; Proteobacteria |
Template | O86262 (TPMT_PSESJ) |
Triggered by |
Identifier |
|
Protein name |
|
Gene name |
|
Catalytic activity | Reaction=S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.; EC=2.1.1.67; |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. |
Pfam | PF05724; TPMT; 1; |
PIRSF | PIRSF023956; Thiopurine_S-methyltransferase; 1; |
TIGRFAMs | TIGR03840; TMPT_Se_Te; 1; |
PROSITE | PS51585; SAM_MT_TPMT; 1; |
From: TPMT_VIBCH (Q9KSN0) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 11 | 11 | S-adenosyl-L-methionine | W | ||||||||
BINDING | 46 | 46 | S-adenosyl-L-methionine; via carbonyl oxygen | [LM] | ||||||||
BINDING | 67 | 67 | S-adenosyl-L-methionine | E | ||||||||
BINDING | 122 | 122 | S-adenosyl-L-methionine | R |
Size range | 213-235 amino acids |
Related rules | None |
Fusion | None |