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Annotation rule MF_00951 |
General rule information
[?]
Accession |
MF_00951 |
Dates |
13-MAR-2013 (Created) 19-NOV-2019 (Last updated, Version 5) |
Scope |
Bacteria; Proteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Transcription antitermination protein RfaH;
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case <OC:Enterobacterales>
Function |
Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains. |
else
Function |
Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. |
end case
Subunit |
Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). |
Similarity |
Belongs to the RfaH family. |
GO:0003677; Molecular function: DNA binding.
GO:0001073; Molecular function: transcription antitermination factor activity, DNA binding.
GO:0031564; Biological process: transcription antitermination.
Additional information
[?]
Size range |
150-224 amino acids |
Related rules |
None |
Fusion |
None |