HAMAP rule MF_01049
General rule information
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Accession | MF_01049 |
Dates | 13-FEB-2003 (Created) 29-SEP-2022 (Last updated, Version 33) |
Name | CaiT |
Scope | Bacteria; Enterobacterales |
Templates | P31553 (CAIT_ECOLI); B4EY22 (CAIT_PROMH): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the exchange of L-carnitine for gamma-butyrobetaine. |
Catalytic activity | RHEA:29427: (R)-carnitine(out) + 4-(trimethylamino)butanoate(in) = (R)-carnitine(in) + 4-(trimethylamino)butanoate(out) |
Pathway | Amine and polyamine metabolism; carnitine metabolism. |
Subunit | Homotrimer. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0044667; Molecular function: (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity.
GO:1902603; Biological process: carnitine transmembrane transport.
GO:0005886; Cellular component: plasma membrane.
GO:1902603; Biological process: carnitine transmembrane transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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General | Transmembrane; -; 12; trigger=yes; |
Additional information
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Size range | 504-505 amino acids |
Related rules | None |
Fusion | None |