HAMAP rule MF_01060
General rule information
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Accession | MF_01060 |
Dates | 2-JUL-2003 (Created) 26-JAN-2023 (Last updated, Version 22) |
Name | Peripl_trehalase |
Scope | Bacteria; Pseudomonadota |
Template | P13482 (TREA_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system. |
Catalytic activity | RHEA:32675: alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose
EC 3.2.1.28 |
case <OC:Enterobacterales>
Subunit | Monomer. |
end case
Subcellular location | Periplasm. |
Similarity | Belongs to the glycosyl hydrolase 37 family. |
Keywords
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Gene Ontology
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GO:0004555; Molecular function: alpha,alpha-trehalase activity.
GO:0005991; Biological process: trehalose metabolic process.
GO:0042597; Cellular component: periplasmic space.
GO:0005991; Biological process: trehalose metabolic process.
GO:0042597; Cellular component: periplasmic space.
Cross-references
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Pfam | PF01204; Trehalase; 1; |
PRINTS | PR00744; GLHYDRLASE37; 1; |
PROSITE | PS00927; TREHALASE_1; 1; |
PS00928; TREHALASE_2; 1; |
Computed features
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General | Signal; -; 1; trigger=yes; |
Features
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From: TREA_ECOLI (P13482) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 159 | 160 | /ligand="substrate | W-D | ||||||||
BINDING | 205 | 207 | /ligand="substrate | [RH]-S-Q | ||||||||
BINDING | 277 | 279 | /ligand="substrate | R-[PQ]-E | ||||||||
ACT_SITE | 312 | 312 | Proton donor/acceptor | D | ||||||||
ACT_SITE | 496 | 496 | Proton donor/acceptor | E | ||||||||
BINDING | 152 | 152 | /ligand="substrate | R | ||||||||
BINDING | 196 | 196 | /ligand="substrate | N | ||||||||
BINDING | 310 | 310 | /ligand="substrate | G | ||||||||
BINDING | 511 | 511 | /ligand="substrate | E |
Additional information
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Size range | 520-660 amino acids |
Related rules | MF_01059 (TREF) |
Fusion | None |