HAMAP rule MF_01062
General rule information
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| Accession | MF_01062 |
| Dates | 4-JUL-2003 (Created)
19-NOV-2022 (Last updated, Version 34) |
| Name | PSRP |
| Scope(s) |
Bacteria |
| Template(s) | P0A8A4 (PSRP_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01062 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PSRP |
| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| Protein name | RecName: Full=Phosphoenolpyruvate synthase regulatory protein; Short=PEP synthase regulatory protein; Short=PSRP; EC=2.7.11.33; EC=2.7.4.28; AltName: Full=Pyruvate, water dikinase regulatory protein; |
| Gene name | Name=ppsR; |
| else | |
| Protein name | RecName: Full=Putative phosphoenolpyruvate synthase regulatory protein; Short=PEP synthase regulatory protein; Short=PSRP; EC=2.7.11.33; EC=2.7.4.28; AltName: Full=Pyruvate, water dikinase regulatory protein; |
| end case | |
Comments
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| FUNCTION | Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. |
| CATALYTIC ACTIVITY | Reaction=[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]- phosphate + AMP + H(+); Xref=Rhea:RHEA:46020, Rhea:RHEA-COMP:11425, Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378, ChEBI:CHEBI:43176, ChEBI:CHEBI:68546, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=2.7.11.33; |
| CATALYTIC ACTIVITY | Reaction=[pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate; Xref=Rhea:RHEA:48580, Rhea:RHEA-COMP:11425, Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:43176, ChEBI:CHEBI:43474, ChEBI:CHEBI:68546; EC=2.7.4.28; |
| SIMILARITY | Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily. |
Keywords
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Gene Ontology
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| GO:0004674; Molecular function:protein serine/threonine kinase activity |
| GO:0016776; Molecular function:phosphotransferase activity, phosphate group as acceptor |
| GO:0043531; Molecular function:ADP binding |
| GO:0006468; Biological process:protein phosphorylation |
| GO:0006470; Biological process:protein dephosphorylation |
Cross-references
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| Pfam | PF03618; Kinase-PPPase; 1; |
Features
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| From: PSRP_ECOLI (P0A8A4) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 157 | 164 | /ligand="ADP" /ligand_id="ChEBI:CHEBI:456216" |
[GA]-x-S-R-x-[GS]-K-[TS] | ||||||||
Additional information
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| Size range | 258-315 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |