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HAMAP rule MF_01062

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General rule information [?]

Accession MF_01062
Dates 4-JUL-2003 (Created)
19-NOV-2022 (Last updated, Version 34)
Name PSRP
Scope(s) Bacteria
Template(s) P0A8A4 (PSRP_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01062 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PSRP
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Protein name RecName: Full=Phosphoenolpyruvate synthase regulatory protein;
                 Short=PEP synthase regulatory protein;
                 Short=PSRP;
                 EC=2.7.11.33;
                 EC=2.7.4.28;
AltName: Full=Pyruvate, water dikinase regulatory protein;
Gene name Name=ppsR;
else
Protein name RecName: Full=Putative phosphoenolpyruvate synthase regulatory protein;
                 Short=PEP synthase regulatory protein;
                 Short=PSRP;
                 EC=2.7.11.33;
                 EC=2.7.4.28;
AltName: Full=Pyruvate, water dikinase regulatory protein;
end case

Comments [?]

FUNCTIONBifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
CATALYTIC ACTIVITY Reaction=[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]- phosphate + AMP + H(+); Xref=Rhea:RHEA:46020, Rhea:RHEA-COMP:11425, Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378, ChEBI:CHEBI:43176, ChEBI:CHEBI:68546, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=2.7.11.33;
CATALYTIC ACTIVITY Reaction=[pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate; Xref=Rhea:RHEA:48580, Rhea:RHEA-COMP:11425, Rhea:RHEA-COMP:11426, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:43176, ChEBI:CHEBI:43474, ChEBI:CHEBI:68546; EC=2.7.4.28;
SIMILARITYBelongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004674; Molecular function:protein serine/threonine kinase activity
GO:0016776; Molecular function:phosphotransferase activity, phosphate group as acceptor
GO:0043531; Molecular function:ADP binding
GO:0006468; Biological process:protein phosphorylation
GO:0006470; Biological process:protein dephosphorylation

Cross-references [?]

Pfam PF03618; Kinase-PPPase; 1;

Features [?]

From: PSRP_ECOLI (P0A8A4)
Key From To Description Tag Condition FTGroup
BINDING 157 164 /ligand="ADP"
/ligand_id="ChEBI:CHEBI:456216"
[GA]-x-S-R-x-[GS]-K-[TS]

Additional information [?]

Size range 258-315 amino acids
Related rules None
Fusion Nter: None Cter: None



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