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Annotation rule MF_01174
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General rule information [?]

Accession MF_01174
Dates 3-NOV-2006 (Created)
21-AUG-2020 (Last updated, Version 17)
Name Aldedh_AstD
Scope
Bacteria; Proteobacteria
Template P76217 (ASTD_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASTD
Protein name
RecName: Full=N-succinylglutamate 5-semialdehyde dehydrogenase;
EC 1.2.1.71;
AltName: Full=Succinylglutamic semialdehyde dehydrogenase;
Short=SGSD;
Gene name
astD

Comments [?]

Function Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
Catalytic activity RHEA:10812: H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + N-succinyl-L-glutamate + NADH
EC 1.2.1.71
Pathway Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5.
Similarity Belongs to the aldehyde dehydrogenase family. AstD subfamily.

Keywords [?]

Arginine metabolism
NAD
Oxidoreductase

Gene Ontology [?]

GO:0016491; Molecular function: oxidoreductase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1;
PS00687; ALDEHYDE_DEHYDR_GLU; 1;
Pfam PF00171; Aldedh; 1;
TIGRFAMs TIGR03240; arg_catab_astD; 1;

Features [?]

From: ASTD_ECOLI (P76217)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     220     225       NAD        
ACT_SITE     243     243             E  
ACT_SITE     277     277             C  

Additional information [?]

Size range 471-505 amino acids
Related rules None
Fusion None


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