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Annotation rule MF_01280
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General rule information [?]

Accession MF_01280
Dates 1-OCT-2007 (Created)
19-NOV-2019 (Last updated, Version 13)
Name Diacylglyc_glucosyltr
Scope
Bacteria; Bacillales
Templates P54166 (UGTP_BACSU); Q5HH69 (UGTP_STAAC); Q2FZP7 (UGTP_STAA8): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
UGTP
case <OC:Bacillus>
Protein name
RecName: Full=Processive diacylglycerol beta-glucosyltransferase;
EC 2.4.1.315;
AltName: Full=Beta-diglucosyldiacylglycerol synthase;
Short=Beta-DGS;
Short=DGlcDAG synthase;
Short=Glc2-DAG synthase;
AltName: Full=Beta-gentiobiosyldiacylglycerol synthase;
AltName: Full=Beta-monoglucosyldiacylglycerol synthase;
Short=Beta-MGS;
Short=MGlcDAG synthase;
AltName: Full=Beta-triglucosyldiacylglycerol synthase;
Short=TGlcDAG synthase;
AltName: Full=Diglucosyl diacylglycerol synthase (1,6-linking);
AltName: Full=Glucosyl-beta-1,6-glucosyldiacylglycerol synthase;
AltName: Full=UDP glucosyltransferase;
AltName: Full=UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase;
else
Protein name
RecName: Full=Processive diacylglycerol beta-glucosyltransferase;
EC 2.4.1.315;
AltName: Full=Beta-diglucosyldiacylglycerol synthase;
Short=Beta-DGS;
Short=DGlcDAG synthase;
Short=Glc2-DAG synthase;
AltName: Full=Beta-gentiobiosyldiacylglycerol synthase;
AltName: Full=Beta-monoglucosyldiacylglycerol synthase;
Short=Beta-MGS;
Short=MGlcDAG synthase;
AltName: Full=Diglucosyl diacylglycerol synthase (1,6-linking);
AltName: Full=Glucosyl-beta-1,6-glucosyldiacylglycerol synthase;
AltName: Full=UDP glucosyltransferase;
AltName: Full=UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase;
end case
Gene name
ugtP

Comments [?]

case <OC:Bacillus>
Function Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
else
Function Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
end case
Catalytic activity RHEA:39031: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP
EC 2.4.1.315
RHEA:17285: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + H(+) + UDP
case <OC:Bacillus>
Catalytic activity RHEA:39027: a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + H(+) + UDP
EC 2.4.1.315
end case
Pathway Glycolipid metabolism; diglucosyl-diacylglycerol biosynthesis.
Subcellular location Cell membrane.
Similarity Belongs to the glycosyltransferase 28 family. UgtP subfamily.

Keywords [?]


Gene Ontology [?]

GO:0035251; Molecular function: UDP-glucosyltransferase activity.
GO:0047228; Molecular function: 1,2-diacylglycerol 3-glucosyltransferase activity.
GO:0009247; Biological process: glycolipid biosynthetic process.
GO:0070395; Biological process: lipoteichoic acid biosynthetic process.

Cross-references [?]

Pfam PF00534; Glycos_transf_1; 1;
PF06925; MGDG_synth; 1;
PF04101; Glyco_tran_28_C; 1;

Additional information [?]

Size range 382-391 amino acids
Related rules None
Fusion None