HAMAP rule MF_01321
General rule information
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Accession | MF_01321 |
Dates | 6-JAN-2004 (Created) 1-JUN-2023 (Last updated, Version 35) |
Name | RNApol_bact_RpoB |
Scope | Bacteria
Plastid |
Templates | Q9KWU7 (RPOB_THEAQ); P0A8V2 (RPOB_ECOLI): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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case not <OG:Chloroplast>
Protein name |
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else case <OG:Chloroplast>
Protein name |
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end case
Gene name |
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Comments
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Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. |
Catalytic activity | RHEA:21248: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
EC 2.7.7.6 |
case not <OG:Chloroplast> and not <OC:Cyanobacteriota>
Subunit | The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. |
else case <OC:Cyanobacteriota>
Subunit | In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. |
else case <OG:Chloroplast>
Subunit | In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. |
Subcellular location | Plastid, chloroplast. |
end case
Similarity | Belongs to the RNA polymerase beta chain family. |
Keywords
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case (<OC:Escherichia> or <OC:Shigella>) and (<FT:1> or <FT:2>)
end case
Gene Ontology
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GO:0003677; Molecular function: DNA binding.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.
GO:0006351; Biological process: DNA-templated transcription.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.
GO:0006351; Biological process: DNA-templated transcription.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case
Cross-references
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Pfam | PF04563; RNA_pol_Rpb2_1; 1; |
PF04561; RNA_pol_Rpb2_2; 1; | |
PF04565; RNA_pol_Rpb2_3; 1; | |
PF00562; RNA_pol_Rpb2_6; 1; | |
PF04560; RNA_pol_Rpb2_7; 1; | |
NCBIfam | TIGR02013; RpoB; 1; |
PROSITE | PS01166; RNA_POL_BETA; 1; |
Features
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case <OC:Escherichia> or <OC:Shigella>
From: RPOB_ECOLI (P0A8V2) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOD_RES | 1022 | 1022 | N6-acetyllysine | K | ||||||||
MOD_RES | 1200 | 1200 | N6-acetyllysine | K |
end case
Additional information
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Size range | 1060-1499 amino acids |
Related rules | None |
Fusion | Nter: None; Cter: MF_01322 (rpoC) |
Comments | Fused with rpoC in Helicobacter species and at least some Wolbachia, but not in other epsilon proteobateria. CHLVU, ODOSI and PSEAK have large inserts, HETCA has a deletion, CHLRE is split. None are used in the alignment. |