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Annotation rule MF_01418
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General rule information [?]

Accession MF_01418
Dates 5-MAR-2004 (Created)
19-NOV-2019 (Last updated, Version 20)
Name SpeB
Scope
Bacteria; Neisseriales
Bacteria; Enterobacterales
Template P60651 (SPEB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SPEB
Protein name
RecName: Full=Agmatinase;
EC 3.5.3.11;
AltName: Full=Agmatine ureohydrolase;
Short=AUH;
Gene name
speB

Comments [?]

Function Catalyzes the formation of putrescine from agmatine.
Catalytic activity RHEA:13929: agmatine + H2O = putrescine + urea
EC 3.5.3.11
Cofactor Mn(2+)
Pathway Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1.
Similarity Belongs to the arginase family. Agmatinase subfamily.

Keywords [?]

Polyamine biosynthesis
Spermidine biosynthesis
Putrescine biosynthesis
Hydrolase
Metal-binding
Manganese

Gene Ontology [?]

GO:0008783; Molecular function: agmatinase activity.
GO:0009446; Biological process: putrescine biosynthetic process.
GO:0008295; Biological process: spermidine biosynthetic process.

Cross-references [?]

Pfam PF00491; Arginase; 1;
TIGRFAMs TIGR01230; Agmatinase; 1;
PROSITE PS01053; ARGINASE_1; 1;
PS51409; ARGINASE_2; 1;

Features [?]

From: SPEB_ECOLI (P60651)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     126     126       Manganese     H  
METAL     149     149       Manganese     D  
METAL     151     151       Manganese     H  
METAL     153     153       Manganese     D  
METAL     230     230       Manganese     D  
METAL     232     232       Manganese     D  

Additional information [?]

Size range 303-322 amino acids
Related rules None
Fusion None
Comments This protein has not been found in Yersinia pestis.


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