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HAMAP rule MF_01498

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General rule information [?]

Accession MF_01498
Dates 11-FEB-2016 (Created)
1-JUN-2023 (Last updated, Version 6)
Name RadA_bact
Scope
Bacteria
Templates P24554 (RADA_ECOLI); P37572 (RADA_BACSU); Q9RVC4 (RADA_DEIRA); Q8DRP0 (RADA_STRR6): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RADA
Protein name
RecName: Full=DNA repair protein RadA;
Gene name
radA

Comments [?]

Function Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
case <FT:1>
Domain Has a putative N-terminal zinc-finger, a middle region with homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.
else
Domain The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.
end case
Similarity Belongs to the RecA family. RadA subfamily.

Keywords [?]

ATP-binding
DNA damage
DNA repair
DNA-binding
Metal-binding
Nucleotide-binding
Stress response
case <FT:1>
Zinc
Zinc-finger
end case

Gene Ontology [?]

GO:0000725; Biological process: recombinational repair.
GO:0005524; Molecular function: ATP binding.

Cross-references [?]

PROSITE PS50162; RECA_2; 1;
Pfam PF05362; Lon_C; 1;
PRINTS PR01874; DNAREPAIRADA; 1;
NCBIfam TIGR00416; sms; 1;

Features [?]

From: RADA_ECOLI (P24554)
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING (Optional)     11     28       C4-type     C-x(2)-C-x(10)-C-x(2)-C  
BINDING     102     109       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     [GAS]-x-P-G-x-G-K-[ST]  
REGION     357     Cter       Lon-protease-like        
MOTIF     258     262       RadA KNRFG motif     K-N-R-[FY]-G  

Additional information [?]

Size range 420-505 amino acids
Related rules None
Fusion None
Comments A number of Streptococcus pneumoniae do not encode the possible zinc-finger. Not a homolog of the archaeal RadA protein.


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