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Annotation rule MF_01558
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General rule information [?]

Accession MF_01558
Dates 12-DEC-2005 (Created)
19-NOV-2019 (Last updated, Version 17)
Name Cyt_deam
Scope
Bacteria; Gammaproteobacteria
Template P0ABF6 (CDD_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CDD
Protein name
RecName: Full=Cytidine deaminase;
EC 3.5.4.5;
AltName: Full=Cytidine aminohydrolase;
Short=CDA;
Gene name
cdd

Comments [?]

Function This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Catalytic activity RHEA:16069: cytidine + H(+) + H2O = NH4(+) + uridine
EC 3.5.4.5
RHEA:13433: 2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)
EC 3.5.4.5
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion.
end case
Subunit Homodimer.
Similarity Belongs to the cytidine and deoxycytidylate deaminase family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0004126; Molecular function: cytidine deaminase activity.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case

Cross-references [?]

Pfam PF00383; dCMP_cyt_deam_1; 1;
PF08211; dCMP_cyt_deam_2; 1;
TIGRFAMs TIGR01355; Cyt_deam_dimer; 1;
PROSITE PS00903; CYT_DCMP_DEAMINASES_1; 1;
PS51747; CYT_DCMP_DEAMINASES_2; 2; trigger=PRU01083;

Features [?]

From: CDD_ECOLI (P0ABF6)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     89     91       Substrate binding     N-x-E  
ACT_SITE     104     104       Proton donor     E  
METAL     102     102       Zinc; catalytic     H   1
METAL     129     129       Zinc; catalytic     C   1
METAL     132     132       Zinc; catalytic     C   1

Additional information [?]

Size range 292-309 amino acids
Related rules None
Fusion None