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Annotation rule MF_01652
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General rule information [?]

Accession MF_01652
Dates 29-APR-2008 (Created)
19-NOV-2019 (Last updated, Version 21)
Name MhpA
Scope
Bacteria; Corynebacteriales
Bacteria; Proteobacteria
Template P77397 (MHPA_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MHPA
Protein name
RecName: Full=3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
Short=3-HCI hydroxylase;
Short=3-HPP hydroxylase;
EC 1.14.13.127;
Gene name
mhpA

Comments [?]

Function Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
Catalytic activity RHEA:24785: 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)
EC 1.14.13.127
RHEA:27846: (2E)-3-(3-hydroxyphenyl)prop-2-enoate + H(+) + NADH + O2 = (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + H2O + NAD(+)
EC 1.14.13.127
Cofactor FAD
Pathway Aromatic compound metabolism; 3-phenylpropanoate degradation.
Similarity Belongs to the PheA/TfdB FAD monooxygenase family.

Keywords [?]

Aromatic hydrocarbons catabolism
FAD
Flavoprotein
NAD
Oxidoreductase

Gene Ontology [?]

GO:0008688; Molecular function: 3-(3-hydroxyphenyl)propionate hydroxylase activity.
GO:0019622; Biological process: 3-(3-hydroxy)phenylpropionate catabolic process.

Cross-references [?]

Pfam PF01494; FAD_binding_3; 1;
PRINTS PR00420; RNGMNOXGNASE; 1;
PR00368; FADPNR; 1;

Features [?]

From: MHPA_ECOLI (P77397)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     17     46       FAD        
NP_BIND     285     295       FAD        

Additional information [?]

Size range 439-622 amino acids
Related rules None
Fusion None


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