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Annotation rule MF_01813 |
General rule information
[?]
Accession |
MF_01813 |
Dates |
6-OCT-2003 (Created) 19-NOV-2019 (Last updated, Version 28) |
Scope |
Bacteria; except Cyanobacteria
Archaea |
case <OC:Bacteria> or <OC:Archaea>
end case
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Proteobacteria>
Protein name |
RecName:
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Full=Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE;
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EC 2.1.1.163;
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EC 2.1.1.201;
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AltName:
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Full=2-methoxy-6-polyprenyl-1,4-benzoquinol methylase;
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AltName:
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Full=Demethylmenaquinone methyltransferase;
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else
Protein name |
RecName:
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Full=Demethylmenaquinone methyltransferase;
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EC 2.1.1.163;
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end case
case <OC:Proteobacteria>
Function |
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). |
Catalytic activity |
RHEA:42640: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.163
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RHEA:28286: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.201
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Pathway |
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2. |
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Cofactor biosynthesis; ubiquinone biosynthesis. |
else
Function |
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). |
Catalytic activity |
RHEA:42640: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.163
|
Pathway |
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2. |
end case
Similarity |
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. |
case <OC:Proteobacteria>
end case
case <OC:Proteobacteria>
GO:0008425; Molecular function: 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity.
GO:0009060; Biological process: aerobic respiration.
end case
GO:0009234; Biological process: menaquinone biosynthetic process.
From: COQ5_YEAST (P49017) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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REGION
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179
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180
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S-adenosyl-L-methionine binding
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[ND]-x
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BINDING
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122
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122
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S-adenosyl-L-methionine
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[ST]
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BINDING
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148
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148
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S-adenosyl-L-methionine
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D
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BINDING
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197
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197
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S-adenosyl-L-methionine
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S
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Additional information
[?]
Size range |
220-352 amino acids |
Related rules |
MF_03192 (MENG supersedes the current rule); MF_01982 (MENG supersedes the current rule) |
Fusion |
None |