Home  |  Contact
Annotation rule MF_01881
Send feedback

General rule information [?]

Accession MF_01881
Dates 23-JUL-2010 (Created)
19-NOV-2019 (Last updated, Version 11)
Name Propion_kin_subfam1
Scope
Bacteria; Enterobacterales
Templates P11868 (TDCD_ECOLI); O06961 (TDCD_SALTY): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TDCD
Protein name
RecName: Full=Propionate kinase;
EC 2.7.2.15;
Gene name
tdcD

Comments [?]

Function Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
Catalytic activity RHEA:23148: ATP + propanoate = ADP + propanoyl phosphate
EC 2.7.2.15
Cofactor Mg(2+)
Pathway Amino-acid degradation; L-threonine degradation via propanoate pathway; propanoate from L-threonine: step 4/4.
Subunit Homodimer.
Similarity Belongs to the acetokinase family. TdcD subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008980; Molecular function: propionate kinase activity.
GO:0016310; Biological process: phosphorylation.

Cross-references [?]

Pfam PF00871; Acetate_kinase; 1;
PRINTS PR00471; ACETATEKNASE; 1;
TIGRFAMs TIGR00016; AckA; 1;
PIRSF PIRSF000722; Acetate_prop_kin; 1;
PROSITE PS01075; ACETATE_KINASE_1; 1;
PS01076; ACETATE_KINASE_2; 1;

Features [?]

From: TDCD_SALTY (O06961)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     203     207       ATP     H-L-G-N-G  
NP_BIND     278     280       ATP     D-[LM]-R  
NP_BIND     326     330       ATP     G-I-G-E-N  
ACT_SITE     143     143       Proton donor/acceptor     D  
METAL     11     11       Magnesium     N  
METAL     381     381       Magnesium     D  
BINDING     11     11       ATP     N  
BINDING     18     18       ATP     K  
BINDING     86     86       Substrate     R  
BINDING     175     175       ATP     H  
BINDING     326     326       ATP; via amide nitrogen     G  
SITE     175     175       Transition state stabilizer     H  
SITE     236     236       Transition state stabilizer     R  

Additional information [?]

Size range 372-418 amino acids
Related rules MF_00020 (ACKA)
Fusion None