HAMAP rule MF_01913

General rule information [?]

Accession	MF_01913
Dates	31-MAR-2014 (Created) 19-NOV-2022 (Last updated, Version 12)

Name	SLA_reductase

Scope

Bacteria; Enterobacterales

Template

P0A9V8 (SQUU_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

SQUU

Protein name

RecName:		Full=3-sulfolactaldehyde reductase;
		Short=SLA reductase;
		EC 1.1.1.373;

Comments [?]

Function	Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).
Catalytic activity	RHEA:40511: (2S)-3-sulfopropanediol + NAD(+) = (2S)-3-sulfolactaldehyde + H(+) + NADH EC 1.1.1.373 PhysiologicalDirection=right-to-left (RHEA:40513)
Similarity	Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.

Keywords [?]

Gene Ontology [?]

GO:0061596; Molecular function: 3-sulfolactaldehyde reductase activity.
GO:1902777; Biological process: 6-sulfoquinovose(1-) catabolic process.

Cross-references [?]

Features [?]

From: SQUU_ECOLI (P0A9V8)

Key From To Description Tag Condition FTGroup

BINDING 11 12 /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540 Q-M

BINDING 174 178 /ligand="2,3-dihydroxypropane-1-sulfonate" /ligand_id="ChEBI:CHEBI:77138 N-N-Y-M-S

ACT_SITE 171 171 K

BINDING 31 31 /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540 D

BINDING 65 65 /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540 L

BINDING 96 96 /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540 T

BINDING 123 123 /ligand="2,3-dihydroxypropane-1-sulfonate" /ligand_id="ChEBI:CHEBI:77138 R

BINDING 240 240 /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540 K

Additional information [?]