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Annotation rule MF_01920
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General rule information [?]

Accession MF_01920
Dates 12-MAY-2014 (Created)
19-NOV-2019 (Last updated, Version 5)
Name Helicase_Rep
Scope
Bacteria; Proteobacteria
Template P09980 (REP_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
REP
Protein name
RecName: Full=ATP-dependent DNA helicase Rep;
EC 3.6.4.12;
Gene name
rep

Comments [?]

Function Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
Catalytic activity RHEA:13065: ATP + H2O = ADP + H(+) + phosphate
EC 3.6.4.12
Subunit Homodimer.
Similarity Belongs to the helicase family. UvrD subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003678; Molecular function: DNA helicase activity.
GO:0005524; Molecular function: ATP binding.
GO:0003697; Molecular function: single-stranded DNA binding.
GO:0006268; Biological process: DNA unwinding involved in DNA replication.

Cross-references [?]

PROSITE PS51198; UVRD_HELICASE_ATP_BIND; 1; trigger=PRU00560;
PS51217; UVRD_HELICASE_CTER; 1; trigger=PRU00617;
Pfam PF00580; UvrD-helicase; 1;
PF13361; UvrD_C; 1;
TIGRFAMs TIGR01074; rep; 1;

Features [?]

From: REP_ECOLI (P09980)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     278     278       ATP     R  

Additional information [?]

Size range 640-750 amino acids
Related rules None
Fusion None