HAMAP rule MF_02063

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02063
Accession	MF_02063
Dates	06-APR-2016 (Created) 08-AUG-2025 (Last updated, Version 8)
Name	GltP_subfam
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P21345; [ Recover all ]
Triggered by	HAMAP; MF_02063 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	GLTP
case <OC:Enterobacterales>
Protein name	RecName: Full=Glutamate/aspartate-proton symporter GltP;
else
Protein name	RecName: Full=Probable glutamate/aspartate-proton symporter GltP;
end case
Gene name	Name=gltP;

Comments [?]

FUNCTION	Catalyzes the proton-dependent transport of glutamate and aspartate. At least two protons are transported in symport with the substrate.
CATALYTIC ACTIVITY	Reaction=L-glutamate(in) + 2 H(+)(in) = L-glutamate(out) + 2 H(+)(out); Xref=Rhea:RHEA:29027, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985;
CATALYTIC ACTIVITY	Reaction=L-aspartate(in) + 2 H(+)(in) = L-aspartate(out) + 2 H(+)(out); Xref=Rhea:RHEA:29287, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991;
SUBUNIT	Homotrimer.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016020; Cellular component:membrane

GO:0005280; Molecular function:amino acid:proton symporter activity

GO:0055085; Biological process:transmembrane transport

Cross-references [?]

Features [?]

Additional information [?]