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Annotation rule MF_02094
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General rule information [?]

Accession MF_02094
Dates 10-OCT-2017 (Created)
20-NOV-2019 (Last updated, Version 3)
Name Edd
Scope
Bacteria
Templates P0ADF6 (EDD_ECOLI); P21909 (EDD_ZYMMO): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
EDD
Protein name
RecName: Full=Phosphogluconate dehydratase;
EC 4.2.1.12;
Gene name
edd

Comments [?]

Function Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.
Catalytic activity RHEA:17277: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O
EC 4.2.1.12
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster
Pathway Carbohydrate metabolism; Entner-Doudoroff pathway.
Similarity Belongs to the IlvD/Edd family.

Keywords [?]


Gene Ontology [?]

GO:0004456; Molecular function: phosphogluconate dehydratase activity.
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0046177; Biological process: D-gluconate catabolic process.
GO:0009255; Biological process: Entner-Doudoroff pathway through 6-phosphogluconate.

Cross-references [?]

PROSITE PS00886; ILVD_EDD_1; 1;
PS00887; ILVD_EDD_2; 1;
Pfam PF00920; ILVD_EDD; 1;
TIGRFAMs TIGR01196; edd; 1;

Features [?]

From: EDD_ECOLI (P0ADF6)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     154     154       Iron-sulfur (4Fe-4S)     C  
METAL     221     221       Iron-sulfur (4Fe-4S)     C  

Additional information [?]

Size range 570-660 amino acids
Related rules None
Fusion None