HAMAP rule MF_03150
General rule information
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Accession | MF_03150 |
Dates | 18-AUG-2011 (Created)
1-JUN-2023 (Last updated, Version 10) |
Name | GatA_euk |
Scope(s) |
Eukaryota |
Template(s) | Q9H0R6 (GATA_HUMAN); Q9LI77 (GATA_ARATH); [ Recover all ] |
Triggered by |
case c? <OC:Eukaryota>
HAMAP; MF_00120 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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Identifier | GATA |
case <OC:Viridiplantae> | |
Protein name | RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial; Short=Glu-AdT subunit A; EC=6.3.5.7; |
else case <OC:Vertebrata> | |
Protein name | RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Short=Glu-AdT subunit A; EC=6.3.5.7; AltName: Full=Glutaminyl-tRNA synthase-like protein 1; |
else | |
Protein name | RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Short=Glu-AdT subunit A; EC=6.3.5.7; |
end case | |
case <OC:Vertebrata> | |
Gene name | Name=QRSL1; |
else case <OC:Saccharomycotina> | |
Gene name | Name=HER2; |
else case <OC:Viridiplantae> | |
Gene name | Name=GATA; |
else case <OC:Insecta> | |
Gene name | Name=GatA; |
end case |
Comments
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case <OC:Viridiplantae> | |
FUNCTION | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). |
else | |
FUNCTION | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). |
end case | |
CATALYTIC ACTIVITY | Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate; Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359, ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216; EC=6.3.5.7; |
case <OC:Vertebrata> | |
SUBUNIT | Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (@gn(QRSL1)), B (@gn(GATB)) and C (@gn(GATC)) subunits. |
else case <OC:Saccharomycotina> | |
SUBUNIT | Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits. |
else | |
SUBUNIT | Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. |
end case | |
case <OC:Viridiplantae> | |
SUBCELLULAR LOCATION | Mitochondrion. Plastid, chloroplast stroma. |
else | |
SUBCELLULAR LOCATION | Mitochondrion. |
end case | |
case <OC:Viridiplantae> | |
MISCELLANEOUS | This protein may be expected to contain an N-terminal transit peptide but none has been predicted. |
end case | |
SIMILARITY | Belongs to the amidase family. GatA subfamily. |
Keywords
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case <OC:Viridiplantae> | |
Chloroplast | |
Plastid | |
end case | |
Mitochondrion | |
ATP-binding | |
Ligase | |
Nucleotide-binding | |
Protein biosynthesis |
Gene Ontology
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case <OCellular component:Viridiplantae> | |
GO:0009507; Cellular component:chloroplast | |
end case | |
GO:0005739; Cellular component:mitochondrion | |
GO:0030956; Cellular component:glutamyl-tRNA(Gln) amidotransferase complex | |
GO:0050567; Molecular function:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | |
GO:0016884; Molecular function:carbon-nitrogen ligase activity, with glutamine as amido-N-donor | |
GO:0070681; Biological process:glutaminyl-tRNAGln biosynthesis via transamidation | |
GO:0032543; Biological process:mitochondrial translation |
Cross-references
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Features
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From: GATA_HUMAN (Q9H0R6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 76 | 76 | /note="Charge relay system" | K | ||||||||
ACT_SITE | 171 | 171 | /note="Charge relay system" | S | ||||||||
ACT_SITE | 195 | 195 | /note="Acyl-ester intermediate" | S |
Additional information
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Size range | 450-550 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |