HAMAP rule MF_03150
General rule information
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Accession | MF_03150 |
Dates | 18-AUG-2011 (Created) 1-JUN-2023 (Last updated, Version 10) |
Name | GatA_euk |
Scope | Eukaryota |
Templates | Q9H0R6 (GATA_HUMAN); Q9LI77 (GATA_ARATH): [Recover all] |
case <OC:Eukaryota>
Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case <OC:Viridiplantae>
Protein name |
|
else case <OC:Vertebrata>
Protein name |
|
else
Protein name |
|
end case
case <OC:Vertebrata>
Gene name |
|
else case <OC:Saccharomycotina>
Gene name |
|
else case <OC:Viridiplantae>
Gene name |
|
else case <OC:Insecta>
Gene name |
|
end case
Comments
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case <OC:Viridiplantae>
Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). |
else
Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). |
end case
Catalytic activity | RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
EC 6.3.5.7 |
case <OC:Vertebrata>
Subunit | Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (@gn(QRSL1)), B (@gn(GATB)) and C (@gn(GATC)) subunits. |
else case <OC:Saccharomycotina>
Subunit | Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits. |
else
Subunit | Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. |
end case
case <OC:Viridiplantae>
Subcellular location | Mitochondrion. Plastid, chloroplast stroma. |
else
Subcellular location | Mitochondrion. |
end case
case <OC:Viridiplantae>
Miscellaneous | This protein may be expected to contain an N-terminal transit peptide but none has been predicted. |
end case
Similarity | Belongs to the amidase family. GatA subfamily. |
Keywords
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case <OC:Viridiplantae>
end case
Gene Ontology
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case <OC:Viridiplantae>
GO:0009507; Cellular component: chloroplast.
end case
GO:0005739; Cellular component: mitochondrion.
GO:0030956; Cellular component: glutamyl-tRNA(Gln) amidotransferase complex.
GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0016884; Molecular function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor.
GO:0070681; Biological process: glutaminyl-tRNAGln biosynthesis via transamidation.
GO:0032543; Biological process: mitochondrial translation.
GO:0030956; Cellular component: glutamyl-tRNA(Gln) amidotransferase complex.
GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0016884; Molecular function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor.
GO:0070681; Biological process: glutaminyl-tRNAGln biosynthesis via transamidation.
GO:0032543; Biological process: mitochondrial translation.
Cross-references
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Features
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From: GATA_HUMAN (Q9H0R6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 76 | 76 | Charge relay system | K | ||||||||
ACT_SITE | 171 | 171 | Charge relay system | S | ||||||||
ACT_SITE | 195 | 195 | Acyl-ester intermediate | S |
Additional information
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Size range | 450-550 amino acids |
Related rules | None |
Fusion | None |